Experienced nephrologist Dr Edgar Lerma explains the inner workings of C3G, how it can affect the kidneys, and the importance of being transparent with your doctor.
This physician received compensation from Novartis Pharmaceuticals Corporation for his time.
What Are the Symptoms of C3G?
C3G can start slowly, continuing to get worse even if you don’t feel unwell
High blood pressure (hypertension)
Swelling of the hands and feet (edema)
Blood in the urine (hematuria)
Foamy urine (proteinuria)
C3G is a progressive kidney disease that may lead to kidney failure
How Is It Managed?
There are no medicines that are FDA approved to treat C3G.
The only medicines available are ones that help slow how fast C3G damages your kidneys, and ones that relieve some of your symptoms.
Your doctor may prescribe certain medications, such as:
Blood pressure medications
Medications for hypertension (high blood pressure) help reduce the amount of protein in your urine. Two common medications are angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs).
Steroids can reduce inflammation and help suppress the immune system's activity. Steroids are prescribed for a wide range of inflammatory and autoimmune diseases.
Your doctor may also ask you to make some lifestyle changes to maintain your overall health
These may include:
Reduce salt intake
The majority of sodium in the body comes from salt, and reducing salt intake can help lower your blood pressure as well as reduce edema (swelling caused by too much fluid).
Regular exercise can improve kidney health by lowering blood pressure, lowering cholesterol, reducing weight, and improving sleep.
Uncontrolled or poorly controlled high blood pressure is a main cause of kidney disease. Some of the medicines used to treat high blood pressure can be affected by smoking. Smoking slows down blood flow to the kidneys and can worsen kidney disease.
Extra weight forces the kidneys to work harder at filtering waste, which can complicate symptoms.