6 types of lupus nephropathy2017-05-07 17:07
Lupus erythematosus nephropathy is an autoimmune disease, in recent years, due to the better detection is negotiable, the prognosis of this disease has been greatly improved, we have the following terms of several types of lupus nephropathy.
For the classification of lupus nephropathy, the WHO divided it into 6 types:
Type I: normal or minimal lesions
Mesangial cell proliferation, mesangial thickening, a small amount of proteinuria and microscopic hematuria, which has a good prognosis
Type III (focal proliferative glomerular involvement): not more than 50%. in glomerular endothelial cells showed segmental proliferation and focal necrosis, there is a small or medium quantity of urine protein, urine rare, hormone treatment reaction, less occurrence of renal failure.
Type IV (diffuse proliferative type): glomerular involvement over 50%. glomerular basement membrane irregular proliferation, extensive necrosis, severe proteinuria, tubular urine and hypertension, poor prognosis
V (film): a mesangium, basement membrane thickening, but no cell proliferation and necrosis. There is often a large number of proteinuria, edema, hypertension and hypercholesterolemia, hypoalbuminemia, hormone therapy between good and bad prognosis changes, eventually developed into renal failure.
Type VI (hardening): glomerular sclerosis, renal failure, poor treatment effect, bad prognosis. The pathological type, each transition and transformation. If the lesion with proliferation, while after treatment may reverse the disease; to cure, treatment effect is poor. Therefore only early treatment can prevent renal failure, systemic lupus erythematosus and can prolong the survival period.
The above described 6 types of lupus nephropathy, lupus erythematosus nephropathy know clinical manifestation, grasp of the several type, to know more about lupus nephropathy, make the patient friends more control over their condition, to maintain a good attitude, to face the treatment of Red Spot lupus nephropathy.
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