The serious harm of weight gain to the kidney2017-10-08 16:50
Glomerular sclerosis caused renal failure: weight gain may lead to hyperlipidemia induced vascular endothelial cell injury and focal loss, resulting in increased vascular permeability, plasma lipoprotein into and deposition in the vessel wall intima, cause macrophage removal reaction and vascular smooth muscle cells proliferation and the formation of plaque, which led to atherosclerosis. Renal arteriosclerosis, stenosis, can cause kidney ischemia, atrophy and interstitial fibrosis hardening.
If the renal vascular obstruction, the corresponding regional infarction, infarction after the formation of epilepsy. This leads to glomerulosclerosis. Outside the kidney, it can accelerate the occurrence of coronary atherosclerosis, lead to coronary heart disease and increase the risk of myocardial infarction, cerebral arteriosclerosis and risk of cerebral infarction.
Glomerular injury lead to kidney necrosis: Hyperlipidemia can cause lipid deposition in glomeruli, low density lipoprotein can activate circulating monocytes, and lead to the infiltration of mononuclear cells in glomeruli, and cause or aggravate the inflammatory reaction, and mesangial cells, glomerular endothelial cells can produce an active oxygen molecule, promote lipid peroxidation, oxidized low density lipoprotein (OX-LDL) has strong cytotoxic effect, causing kidney damage, even necrosis.
Exercise can reduce blood lipid lowering the burden of kidney nourishing effect can be achieved.
As everyone knows, hyperlipidemia and low HDL hyperlipidemia is the most dangerous factor of atherosclerosis, and obesity is often associated with abnormal lipid metabolism, hyperlipidemia is obvious; at the same time promote the excessive accumulation of fat, forming a vicious spiral.
The body's fat can be pided into: body fat, cold fat, significant central obesity, obvious limbs slightly obese; upper body fat accumulation more upper body fat; lower body fat accumulation more lower body fat. Hyperlipidemia and diabetes are mainly associated with central obesity and upper body obesity, so it is helpful to reduce blood lipids by adhering to exercise and healthy weight loss.
Diet should be based on light, cooking oil, mainly vegetable oil. Limit calories, eat sweets, nuts, cakes, barbecue, fried, etc., to strengthen the campaign, increase consumption, quit smoking wine, avoid excessive tension, life should be regular.
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