Factors that influence glomerular filtration rate2017-09-22 15:01
Glomerular filtration rate (GFR) refers to the unit time (usually 1min) within the two kidney to produce the amount of filtrate, the normal adult 80-120ml / min or so. The ratio of glomerular filtration rate to renal plasma flow is called the filtration fraction. Flow through the kidney about 1/5 from the glomerular filtration into the capsule cavity of the original urine. Glomerular filtration rate and filtration fraction are indicators of renal function. The following is the impact of glomerular filtration rate of the factors introduced, we hope to help.
Factors that influence glomerular filtration rate
Glomerular filtration membrane area and permeability of glomerular filtration rate is one of the factors. When the filtration area is reduced, the glomerular filtration rate will be reduced, leading to the occurrence of oliguria; and filtration membrane permeability will appear proteinuria and hematuria, resulting in damage to the kidneys.
Factors affecting glomerular filtration rate. Effective filter pressure aluminum pot effect of power, equal to glomerular capillary blood pressure - (intracystic blood pressure + plasma colloid osmotic pressure), any one of the changes, will affect the glomerular filtration rate. Plasma colloid osmotic pressure decreased, effective filtration pressure increased glomerular filtration rate increased, increased urine output. Capsule pressure will be due to urinary tract obstruction and increased, so that effective filtration pressure is reduced, decreased glomerular filtration rate, oliguria.
Renal plasma flow is also one of the factors affecting glomerular filtration rate, renal plasma flow will affect the number of plasma colloid osmotic pressure in the glomerular capillary flow through the speed. The more plasma flow, plasma colloid osmotic pressure increased more slowly, so that the effective increase in glomerular filtration area, increased glomerular filtration rate and polyuria. vice versa.
The above describes the factors affecting the glomerular filtration rate, I believe we have a certain understanding, we hope to help you. If you have any other questions, please consult our online doctor or give us a message, we will reply to you as soon as possible.
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